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Q Ping Dou Selected Research

Proteasome Endopeptidase Complex (Proteasome)

1/2021Repurposing old drugs as new inhibitors of the ubiquitin-proteasome pathway for cancer treatment.
1/2021Targeting Ubiquitin-Proteasome System With Copper Complexes for Cancer Therapy.
1/2021Synthesis and evaluation of tiaprofenic acid-derived UCHL5 deubiquitinase inhibitors.
1/2020Updated Review and Perspective on 20S Proteasome Inhibitors in the Treatment of Lung Cancer.
1/2019An Updated Review of Disulfiram: Molecular Targets and Strategies for Cancer Treatment.
7/2018In vitro and in vivo studies of gold(I) azolate/phosphane complexes for the treatment of basal like breast cancer.
2/2018Discovery of Natural Proteasome Inhibitors as Novel Anticancer Therapeutics: Current Status and Perspectives.
1/2018Growth arrest and apoptosis induction in androgen receptor-positive human breast cancer cells by inhibition of USP14-mediated androgen receptor deubiquitination.
12/2017Targeting the ubiquitin-proteasome system for cancer treatment: discovering novel inhibitors from nature and drug repurposing.
2/2017Repurposing an antidandruff agent to treating cancer: zinc pyrithione inhibits tumor growth via targeting proteasome-associated deubiquitinases.
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Q Ping Dou Research Topics

Disease

172Neoplasms (Cancer)
05/2022 - 06/2002
45Prostatic Neoplasms (Prostate Cancer)
07/2018 - 07/2002
43Breast Neoplasms (Breast Cancer)
11/2019 - 08/2003
18Multiple Myeloma
01/2020 - 08/2002
16Leukemia
02/2011 - 06/2002
8Neoplasm Metastasis (Metastasis)
01/2022 - 11/2002
7Hematologic Neoplasms (Hematological Malignancy)
01/2017 - 12/2006
6Carcinogenesis
01/2022 - 05/2005
5Hepatocellular Carcinoma (Hepatoma)
05/2022 - 06/2004
5Inflammation (Inflammations)
10/2021 - 01/2008
4Lung Neoplasms (Lung Cancer)
11/2021 - 05/2009
4Alcoholism (Alcohol Abuse)
12/2017 - 11/2006
4Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
02/2017 - 12/2011
4Carcinoma (Carcinomatosis)
06/2013 - 07/2003
3Pancreatic Neoplasms (Pancreatic Cancer)
01/2017 - 08/2009
3Lymphoma (Lymphomas)
01/2014 - 05/2005
3Alzheimer Disease (Alzheimer's Disease)
02/2007 - 01/2005
3Head and Neck Neoplasms (Head and Neck Cancer)
05/2005 - 06/2002
2Drug-Related Side Effects and Adverse Reactions
01/2021 - 12/2017

Drug/Important Bio-Agent (IBA)

105Proteasome Endopeptidase Complex (Proteasome)IBA
01/2021 - 07/2002
60Proteasome InhibitorsIBA
01/2021 - 07/2002
42Proteins (Proteins, Gene)FDA Link
01/2021 - 07/2002
41CopperIBA
01/2022 - 03/2004
28Pharmaceutical PreparationsIBA
05/2022 - 08/2002
27TeaIBA
01/2022 - 07/2002
27PolyphenolsIBA
01/2022 - 10/2002
25ChymotrypsinFDA Link
01/2015 - 07/2002
24Bortezomib (Velcade)FDA Link
01/2021 - 08/2002
24UbiquitinIBA
01/2021 - 08/2002
16Androgen Receptors (Androgen Receptor)IBA
07/2018 - 08/2006
16Biological ProductsIBA
01/2017 - 09/2004
15Ubiquitinated ProteinsIBA
01/2015 - 09/2003
14MetalsIBA
01/2022 - 10/2007
13ATP dependent 26S protease (26S proteasome)IBA
05/2014 - 07/2002
12epigallocatechin gallate (epigallocatechin-3-gallate)IBA
01/2022 - 10/2002
12LigandsIBA
06/2013 - 03/2004
11Cisplatin (Platino)FDA LinkGeneric
11/2018 - 11/2006
11AndrogensIBA
06/2014 - 12/2006
10Disulfiram (Antabuse)FDA Link
01/2019 - 11/2006
10ProdrugsIBA
11/2018 - 09/2004
8GoldIBA
08/2021 - 11/2006
8Deubiquitinating EnzymesIBA
11/2019 - 01/2014
7Antineoplastic Agents (Antineoplastics)IBA
01/2021 - 05/2007
7Clioquinol (Vioform)FDA Link
01/2020 - 01/2005
7Schiff Bases (Schiff Base)IBA
01/2015 - 11/2006
7CaspasesIBA
04/2014 - 07/2002
7Hormones (Hormone)IBA
12/2012 - 08/2006
7CurcuminIBA
01/2012 - 12/2006
6FlavonoidsIBA
02/2021 - 05/2005
6Ditiocarb (Sodium Diethyldithiocarbamate)FDA Link
12/2017 - 05/2007
6Caspase 3 (Caspase-3)IBA
01/2014 - 08/2003
6pyrrolidine dithiocarbamic acidIBA
01/2011 - 01/2005
5DNA (Deoxyribonucleic Acid)IBA
01/2022 - 01/2004
5EnzymesIBA
01/2021 - 05/2014
5ZincIBA
01/2020 - 08/2008
5CadmiumIBA
07/2018 - 06/2008
5Peptide Hydrolases (Proteases)FDA Link
06/2014 - 11/2002
5GenisteinIBA
05/2012 - 09/2003
5ApigeninIBA
10/2008 - 05/2005
5beta-LactamsIBA
09/2008 - 06/2002
5beta Lactam AntibioticsIBA
09/2008 - 06/2002
4carfilzomibIBA
01/2021 - 01/2015
4Metformin (Glucophage)FDA LinkGeneric
01/2021 - 05/2012
4Estrogen ReceptorsIBA
11/2019 - 05/2007
4Phosphotransferases (Kinase)IBA
08/2015 - 11/2002
4Coordination ComplexesIBA
06/2014 - 08/2008
4gambogic acidIBA
04/2014 - 02/2011
4Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
04/2014 - 01/2004
4QuercetinIBA
05/2012 - 05/2005
4prolinedithiocarbamate (PDTC)IBA
01/2011 - 01/2005
4NF-kappa B (NF-kB)IBA
06/2010 - 09/2003
4Anti-Bacterial Agents (Antibiotics)IBA
09/2009 - 06/2002
4AntioxidantsIBA
01/2009 - 11/2002
4NF-KappaB Inhibitor alphaIBA
11/2008 - 07/2002
3Histones (Histone)IBA
01/2022 - 01/2012
3Auranofin (Ridaura)FDA Link
08/2021 - 10/2014
3Cysteine (L-Cysteine)FDA Link
11/2019 - 04/2014
3Reactive Oxygen Species (Oxygen Radicals)IBA
01/2019 - 07/2010
3CarcinogensIBA
07/2018 - 06/2008
3Histone Deacetylase InhibitorsIBA
01/2016 - 01/2012
3Small Interfering RNA (siRNA)IBA
08/2015 - 12/2013
3AMP-Activated Protein KinasesIBA
06/2014 - 01/2012
3withaferin AIBA
01/2014 - 02/2007
3Aldehyde DehydrogenaseIBA
01/2014 - 11/2006
3celastrolIBA
01/2014 - 05/2006
33,3'-diindolylmethane (diindolylmethane)IBA
01/2012 - 07/2007
3Oxyquinoline (8 Hydroxyquinoline)FDA Link
02/2010 - 01/2005
3EstersIBA
01/2009 - 06/2004
3CalpainIBA
12/2008 - 08/2003
3LuteolinIBA
10/2008 - 01/2007
3I-kappa B Proteins (I kappa B)IBA
01/2008 - 07/2002
3Interleukin-2 Receptor alpha SubunitIBA
05/2005 - 07/2003
2bcl-2-Associated X Protein (bcl 2 Associated X Protein)IBA
08/2021 - 07/2002
2ixazomibIBA
01/2021 - 01/2014
2Heat-Shock Proteins (Heat-Shock Protein)IBA
01/2020 - 12/2015
2Ubiquitin-Specific ProteasesIBA
11/2019 - 01/2018

Therapy/Procedure

62Therapeutics
01/2022 - 01/2003
19Drug Therapy (Chemotherapy)
01/2020 - 11/2005
3Chemoprevention
01/2022 - 10/2008
3Chinese Traditional Medicine (Traditional Chinese Medicine)
06/2020 - 05/2009